Sensing platform for nucleic-acid detection based on a 2-aminopurine probe sheared by trans-cleavage activity of the CRISPR/Cas12a system
Analyst, 2023, 148,2482-2492DOI: 10.1039/D3AN00502J, PaperXiaolong Chen, Chaowang Huang, Qiao Hu, Jing Zhang, Dan Wang, Qianyi You, Mingdong HuA 2-AP probe is used to replace ssDNA-FQ in the classical CRISPR/Cas12 system, realizing the highly sensitive…